Inflammatory Linear Verrucous Epidermal Nevus is a rare disease of the skin that presents as multiple, discrete, red papules that tend to coalesce into linear plaques that follow the Lines of Blaschko. The plaques can be slightly warty (psoriaform) or scaly (eczema-like). ILVEN is caused by somatic mutations that result in genetic mosaicism. There is no cure, but different medical treatments can alleviate the symptoms.
Linear epidermal nevi ― 一名年輕女孩的右上臂上出現了 Blaschko 的病變痕跡。
Inflammatory linear verrucous epidermal nevi (ILVEN，發炎性線狀疣狀表皮痣)
典型案例
Inflammatory linear verrucous epidermal nevi(炎症性線狀疣狀表皮痣) (ILVEN)
Inflammatory linear verrucous epidermal nevi（炎症性線狀疣狀表皮痣）(ILVEN)
患者於5個月大時首次出現右前額頭皮的黃色斑塊。6個月後，右後側頭皮出現色素沉著的疣狀丘疹。過去5年，這些斑點逐漸增大，但僅限於右側臉部、頭皮及頸部。無疼痛、無癢感，生長發育正常。右臉頰與前額呈輕度隆起的黃色斑塊，向頭皮正面及側面延伸。與斑塊相連的色素沉著疣狀丘疹，從頭皮後部至右側頸部後方形成一條線狀分布。 The patient first showed up at five months old with yellow patches on the right front of the scalp. By six months, they had hyperpigmented verrucous papules on the back right side of the scalp. Over the past five years, these spots slowly grew bigger but stayed only on the right side of the face, scalp, and neck. They aren't painful or itchy, and the patient is growing normally. The right cheek and forehead have slightly raised, yellow patches that stretch onto the front and side of the scalp. Connected to these patches are hyperpigmented, verrucous papules, forming lines from the back of the scalp to the back of the neck on the right side.
○ 診斷與治療
因為疣的形狀相似，需加以區分。表皮痣可透過雷射消融術予以去除。