Poikiloderma
https://en.wikipedia.org/wiki/Poikiloderma
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References
Diagnosis and Differential Diagnosis of Poikiloderma of Civatte: A Dermoscopy Cohort Study 36892344 NIH
Ang Poikiloderma of Civatte ay isang pangkaraniwang kondisyon ng balat na karaniwang lumilitaw sa leeg at mukha, lalo na sa mga babaeng may katamtamang kulay ng balat at nasa postmenopausal na yugto. Ito ay nagpapakita ng halo ng mga pulang guhit, dark spot, at manipis na balat. Kadalasan, apektado nito ang mga bahagi ng katawan na madalas na nalalantad sa araw—tulad ng mukha, leeg, at dibdib—ngunit hindi ang mga bahagi na nakatago sa araw. Maaaring ikategorya ang Poikiloderma of Civatte batay sa pangunahing tampok nito: pamumula, dark spot, o kombinasyon ng pareho. Ang eksaktong sanhi ay hindi pa ganap na nauunawaan, subalit itinuturing na may kinalaman ang matagal na pagkakalantad sa araw, mga pagbabago sa hormonal, mga reaksiyon sa pabango o kosmetiko, at pagtanda. Ang Poikiloderma of Civatte ay maaaring unti‑unting lumala sa paglipas ng panahon.
Poikiloderma of Civatte (PC) is a rather common benign dermatosis of the neck and face, mainly affecting fair-skinned individuals, especially postmenopausal females. It is characterized by a combination of a reticular pattern of linear telangiectasia, mottled hyperpigmentation and superficial atrophy. Clinically, it involves symmetrically sun-exposed areas of the face, the neck, and the V-shaped area of the chest, invariably sparing the anatomically shaded areas. Depending on the prevalent clinical feature, PC can be classified into erythemato-telangiectatic, pigmented, and mixed clinical types. The etiopathogenesis of PC is incompletely understood. Exposure to ultraviolet radiation, hormonal changes of menopause, contact sensitization to perfumes and cosmetics, and normal ageing have been incriminated. The diagnosis is usually clinical and can be confirmed by histology, which is characteristic, but not pathognomonic. The course is slowly progressive and irreversible, often causing significant cosmetic disfigurement.