Karagdagang informasiyon ― Filipino

Ang Keratoacanthoma (KA) ay isang karaniwang tumor sa balat na kilala sa mabilis na paglaki nito at potensyal na mag-regress nang mag-isa. Karaniwang nangyayari ito sa mga matatandang lalaking maputi ang balat na may kasaysayan ng pinsala dulot ng araw. Habang ang surgical removal gamit ang excision o Mohs micrographic surgery ay ang karaniwang paggamot, mayroong iba't ibang opsyon sa therapy na magagamit.
Keratoacanthoma (KA) is a common cutaneous tumor characterized by rapid growth and possible spontaneous regression. It most commonly affects older, fair-skinned males with significantly sun damaged skin. Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.

Ang Keratoacanthoma (KA) ay isang mababang antas na tumor na nagmumula sa ilang glandula ng balat at nagmumukhang katulad ng squamous cell carcinoma (SCC) sa mikroskopyo. May patuloy na debate kung dapat bang ituring ang KA bilang isang anyo ng invasive na SCC.
Keratoacanthoma (KA) is a comparatively common low-grade tumor that initiates in the pilo-sebaceous glands and pathologically mimics squamous cell carcinoma (SCC). Essentially, strong debates confirm classifying keratoacanthoma as a variant of invasive SCC. The clinical behavior of KA is hardly predictable and the differential diagnosis of keratoacanthoma and other conditions with keratoacanthoma-like pseudocarcinomatous epithelial hyperplasia is challenging, both clinically and histopathologically.

Ang Cutaneous squamous cell carcinoma (cSCC) ay ang pangalawang pinaka‑karaniwang uri ng kanser sa mga tao, lalo na sa mga matatandang indibidwal. Karaniwang ginagamit ang operasyon upang gamutin ang cSCC, ngunit para sa ilang pasyente na hindi maaaring magpaopera o ay pumili ng hindi magpaopera, maaaring isaalang‑alang ang iba pang mga opsyon tulad ng mga intralesional na paggamot. Ginamit ang mga tradisyunal na intralesional na paggamot (methotrexate or 5-fluorouracil), ngunit may patuloy na pananaliksik sa mga bagong diskarte tulad ng intralesional immunotherapy at oncolytic virotherapy. Dito, titingnan natin ang iba't ibang intralesional na paggamot para sa cSCC, mula sa mga klasikong pamamaraan hanggang sa mga makabagong diskarte.
Cutaneous squamous cell carcinoma (cSCC) is the second most frequent cancer in humans, and it is especially common in fragile, elderly people. Surgery is the standard treatment for cSCC but intralesional treatments can be an alternative in those patients who are either not candidates or refuse to undergo surgery. Classic intralesional treatments, including methotrexate or 5-fluorouracil, have been implemented, but there is now a landscape of active research to incorporate intralesional immunotherapy and oncolytic virotherapy into the scene, which might change the way we deal with cSCC in the future. In this review, we focus on intralesional treatments for cSCC (including keratoacanthoma), from classic to very novel strategies.