Intraepithelial Carcinoma (Lefu La Bowen) (Intraepithelial carcinoma (Bowen disease)) e bonts'a lisele tsa squamous tse sa tloaelehang li ata ka har'a botenya bohle ba epidermis. Hlahala eohle e koalehile ka har'a epidermis 'me ha e kene ka har'a letlalo. Lefu lena ka botekgeniki le hlalosoa e le mofetše, empa ha le hlase ho fapana le mofets'e o tloaelehileng. (ke hore ke mofetše o nang le ponelopele e ntle.)
Hangata e hlaha e le erythematous, scaly kapa crusty sebakeng sefe kapa sefe 'meleng. Sebaka se tloaelehileng haholo ke maoto a tlaase.
E ka phekoleha ka mekhoa e fapaneng ea kalafo e kang cryotherapy, curettage, cautery, photodynamic therapy, kapa excision ea lesion.
Squamous-cell skin cancer is one of the main types of skin cancer along with basal cell cancer, and melanoma. It usually presents as a hard lump with a scaly top but can also form an ulcer. Onset is often over months. Squamous-cell skin cancer is more likely to spread to distant areas than basal cell cancer. When confined to the outermost layer of the skin, a precancerous or in situ form of cSCC is known as Bowen's disease.
Boemo bo tlwaelehileng ― Intraepithelial Carcinoma (Lefu La Bowen) (Intraepithelial carcinoma (Bowen disease)) e ka nna ya hlahlojwa hampe e le eczema e tšoarellang nako e telele, e sa hlohloneng.
Horn ya letlalo (cutaneous horn) ― Ho fapana le li‑warts, e hlahisa e le nodule e thata, ’me biopsy e ea hlokahala ho qhelela lefu le kotsi.
Haeba leqeba le tšoarella nako e telele, ho lokela ho nahanoa ka kankere ea letlalo.
Intraepithelial carcinoma (Lefu la Bowen (Bowen disease)) ― Nyeoe e tloaelehileng
Tabeng ena, irritated seborrheic keratosis ka boela ea nkoa e le tlhahlobo e ka bang teng ea phapang.
Hangata e nkoa e le phoso ea ho kula (mohlala, eczema e nummular (nummular eczema)).
Intraepithelial Carcinoma (Bolwetsi ba Bowen (Bowen disease)) (Intraepithelial carcinoma (Bowen disease)) ― Nyeoe e tloaelehileng
Nyeoe e 'ngoe e tloaelehileng e fana ka likarolo tse tšoanang tsa morphological ho maemo a ho kula.
Bowen's disease (BD) ke mofuta oa mofetše oa letlalo o qalang karolong e ka ntle ea letlalo (epidermis). E atile haholo ho Caucasians mme hangata e hlaha libakeng tse hlasetsoeng ke letsatsi, empa e ka hlaha le libakeng tse ling. BD hangata e hlaha e le leqeba le le leng. Hangata BD e nkoa e le letšoao la temoso pele ho hlaha mofuta o tebileng haholoanyane oa kankere ea letlalo. Ho hlahloba BD, hangata lingaka li itšetlehile ka ho hlahloba lisampole tsa lisele tlas'a microscope (biopsy). Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease haholo-holo e ama batho ba basoeu (white) ba lilemo tse fetang 60. Lintlha tse ka sehloohong tsa kotsi li kenyelletsa ho ba letsatsing ka nako e telele, ho fokola ha sesole sa 'mele, ho peperehela arsenic, le tšoaetso ea HPV ea letlalo. Mefuta ea HPV ea 16, 18, 34, le 48 e amahanngoa le lefu la Bowen libakeng tsa thobalano. Ho kenya letsoho ha HPV maemong ao e seng litho tsa botona le botšehali ha hoa hlaka. Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Hangata e hlaha e le erythematous, scaly kapa crusty sebakeng sefe kapa sefe 'meleng. Sebaka se tloaelehileng haholo ke maoto a tlaase.
E ka phekoleha ka mekhoa e fapaneng ea kalafo e kang cryotherapy, curettage, cautery, photodynamic therapy, kapa excision ea lesion.
○ Tlhahlobo le Kalafo
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy