Intraepithelial carcinoma (Bowen disease) - Mate Pukupuku Intraepithelial (Mate Bowen)

https://en.wikipedia.org/wiki/Squamous_cell_skin_cancer

E whakaatu ana te Mate Pukupuku Intraepithelial (Mate Bowen) (Intraepithelial carcinoma (Bowen disease)) ka tipu haere nga pūtau squamous atypical puta noa i te matotoru katoa o te epidermis. Ko te puku katoa ka herea ki te epidermis, karekau e uru ki roto i te kiri. Ko tenei mate ka tohua he mate pukupuku, engari kaore i te whakaeke i nga mate pukupuku noa. (arā, he mate pukupuku he pai te tohu.)

I te nuinga o te wa ka puta he waahi erythematous, kirikiri, kirikiri ranei i nga waahi katoa o te tinana. Ko te waahi nui ko nga waewae o raro.

Ka taea te rongoa e nga momo maimoatanga penei i te cryotherapy, curettage, cautery, photodynamic therapy, te tangohanga ranei o te whiu.

○ Taatari me te Maimoatanga
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy

Ētahi atu korero ― Maori

Take angamaheni ― Mate Pukupuku Intraepithelial (Mate Bowen) (Intraepithelial carcinoma (Bowen disease)) tera pea ka pohehehia he kirikiri karekau he mamae.
Kōhatu kiri (cutaneous horn) ― Kaore i rite ki nga kiritona, ka puta mai he nodule pakeke, me te biopsy hei aukati i te mate kino.
Ki te mau tonu te patunga mō te wā roa, me whakaaro ki te mate kanapa kiri (skin cancer).
Mate Pukupuku Intraepithelial (Intraepithelial carcinoma) – Mate Bowen (Bowen disease) ― Puhi angamaheni

I tenei keehi, ka kiia pea ko Irritated seborrheic keratosis he tātaritanga rereke pea.
He maha nga wā ka pohehe mō te mate pūkōrero o te kiri (skin cancer) (hei tauira, nummular eczema).
Carcinoma intraepithelial (Bowen disease) ― Puhi angamaheni
Ko te kāreka intraepithelial (Bowen disease) e tohu ana i ngā pūtau squamous atypical e toro ana i te katoa o te uhi. Ka noho pērā te kōmaka ki te uhi anake, kāore e uru ki te dermis. Ahakoa he kāreka, kāore e raru ana—pērā i te nuinga o ngā kāreka—nā reira he matakite pai. Ka puta te āhua kōwhai (erythematous), kōwhai, he kākau (scaly) rānei, kōwhai, he kākau, he kākau (crusted) i ngā wāhi katoa o te tinana, engari he tino noa i ngā waewae iho. Ka taea te whakaora mā ngā rerekētanga rongoā pēnei i te cryotherapy, curettage, cautery, photodynamic therapy, me te excision o te āhua. ### Diagnosis and Treatment - Dermoscopy - Skin biopsy - Mohs surgery - Photodynamic therapy He kōrero anō – Squamous‑cell skin cancer (cSCC) he momo nui o te kāreka kiri, ā, he mea nui ki te basal cell cancer me te melanoma. Ka puta he pukupuku mārō (hard lump) me te kākau (scaly) i runga, ā, ka taea hoki te ulcer. He nui ake te tūpono ka hora ki ngā wāhi tawhiti i te basal cell cancer. Ina noho ki te outermost layer of the skin, ko te āhua in situ o te cSCC e kīia ana ko Bowen's disease. #### Tauira tipitipiti - Ka taea te hē whakatau i te Intraepithelial carcinoma (Bowen disease) hei eczema (non‑itchy eczema) roa te wā. - Cutaneous horn – kāore i ōrite ki ngā warts, he nodule mārō, me te biopsy hei tirotiro i te kāreka. - Mēnā ka roa te wharanga, me whakaaro ki te kāreka kiri. - I tētahi tauira, ka whakaarohia hoki te seborrheic keratosis i te mea he differential diagnosis. - He maha te hē whakatau ki te allergic disorder, pērā i te nummular eczema. - He tauira anō e whakaatu ana i ngā āhuatanga rite ki ngā āhuatanga allergic.

Rapu whakaahua

References

Bowen's Disease 35287414

NIH

Ko te Bowen's disease (BD) he momo mate pukupuku kiri ka timata i te paparanga o waho o te kiri (epidermis) . He nui ake i nga Caucasians, he maha nga wa ka puta ki nga waahi e marama ana te ra, engari ka puta ano ki etahi atu waahi. I te nuinga o te wa ka puta te BD hei whiu kotahi. Ka kitea te BD hei tohu whakatupato i mua i te whakawhanaketanga o te momo mate pukupuku kiri. Hei whakatau i te mate BD, ko te tikanga ka whakawhirinaki nga taakuta ki te tirotiro i nga tauira kiko i raro i te karu (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.

Bowen disease - Case reports 17001052

NIH

Bowen's disease te nuinga ka pa ki nga tangata mā kua neke ake i te 60. Ko nga mea nui mōrearea ko te whakamāramatanga o te rā (sun exposure) mo te wā roa, te ngoikore o te pūnaha mate (immunosuppression), te rongo arsenic (arsenic exposure), me te mate HPV (HPV infection). Ko nga riu HPV 16, 18, 34, me te 48 e hono ana ki te mate a Bowen i nga wāhi taihemahema (genital sites). Ko te whai wāhi i roto i nga kīvi (lesions) kore ira (non‑genital) he iti ake te mārama.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.