Informationes plurimae ― Latine

Juvenile xanthogranuloma (JXG) satis communis est et frequentissimum genus non‑Langerhans cell histiocytic disorder in pueris. Circiter 75 % casuum hae laesiones intra primum annum vitae apparent, et plus 15‑20 % aegrorum a nativitate habent. Dum rarior in adultis, JXG typice occurrit frequentius in hominibus nuper viginti ad triginta, et aegroti adulti unam vitium habent. Apparet simplex vel multiplex flavo‑orange‑brunneis maculis vel massis, maxime in facie, collo, et parte superiori corporis. Laesiones orales inusitatae sunt, sed massae luteae in lateribus linguae vel alibi in ore apparere possunt, interdum ulcerationes et sanguinem inducentes. Laesiones cutis plerumque signa non faciunt et per aliquot annos in se resolvunt. Tametsi rara, implicatio ocularis est frequentissima extra cutem, deinde pulmonis concursum. Ocular JXG typice unum tantum oculum afficit et in minus quam 0,5 % aegrorum contingit, quamquam circiter 40 % eorum qui ocularia implicatio habent etiam laesiones cutis praecognitas habent.
Juvenile xanthogranuloma (JXG) is a relatively common entity and is the most common form of non-Langerhans cell histiocytic disorder of childhood., It is estimated that in 75% of cases, lesions appear during the first year of life, with >15-20% of patients having lesions at birth. JXG is rare in adults, with a peak incidence in the late twenties to thirties. The majority of adult patients have solitary lesions. Typically, the clinical presentation consists of solitary or multiple yellow-orange-brown firm papules or nodules. The most common locations are the face, neck, and upper torso. Oral lesions are rare and often occur as a yellow nodule on the lateral aspects of the tongue. Oral lesions can also arise on the gingival, buccal mucosa, and midline hard palate and may ulcerate and bleed. Cutaneous lesions are usually asymptomatic, and most lesions spontaneously involute over the course of several years. Although occurring rarely, ocular involvement is the most common extracutaneous site involved, followed by the lungs. Ocular JXG is nearly always unilateral and develops in less than 0.5% of patients. Approximately 40% of patients with ocular JXG, however, have multiple cutaneous lesions at the time of diagnosis.

Juvenile xanthogranulomas (JXGs) sunt rari morbi benigni, qui non‑Langerhans cell histiocytoses maioris generis constituunt. Plerumque massam unam vel plures rubras vel flavescentes ostendunt, saepe in capite vel collo repertae. Plurima JXGs vel in nativitate vel in primo anno vitae evolvuntur. Dum insolitum est, interdum etiam regiones extra cutem afficere possunt; cum oculi implicati sunt, oportet observare secundum litteras exstantis. Fere JXGs in cute se resolvunt et typice curatione non egent.
Juvenile xanthogranulomas (JXGs) are uncommon, benign diseases that are part of a larger category of non-Langerhans cell histiocytoses. They typically show up as one or more red or yellowish lumps, often found on the head or neck. Most JXGs develop either at birth or within the first year of life. While it's unusual, sometimes they can affect areas beyond the skin, with eye involvement being something to watch for according to existing literature. Generally, JXGs on the skin go away on their own and typically don't need treatment.