Acne - Kukul https://en.wikipedia.org/wiki/Acne
Kukul (Acne) dumadi saka sel kulit mati lan lenga saka kulit menyumbat folikel rambut. Fitur khas saka kondhisi kasebut kalebu komedo utawa komedo putih, kukul, lan kulit berminyak. Utamane mengaruhi kulit kanthi jumlah kelenjar minyak sing relatif dhuwur, kalebu pasuryan, sisih ndhuwur dada, lan mburi. Kukul umume ana ing remaja lan kena pengaruh kira‑kira 80‑90 % remaja ing donya Kulon. Sawetara masyarakat deso nglaporake tingkat kukul sing luwih murah tinimbang sing industri.

Ing loro jinis, hormon sing disebut androgen katon minangka bagéan saka mekanisme dhasar, kanthi nyebabake produksi sebum tambah. Faktor umum liyane yaiku pertumbuhan gedhe saka bakteri Cutibacterium acnes, sing ana ing kulit.

Pangobatan sing ditrapake langsung menyang kulit sing kena pengaruh, kayata azelaic acid, benzoyl peroxide, lan salicylic acid, umume digunakake. Antibiotics lan retinoids kasedhiya ing formulasi sing ditrapake ing kulit lan dijupuk kanthi lisan kanggo perawatan kukul. Nanging, resistensi kanggo antibiotics bisa berkembang minangka asil saka terapi antibiotics. Sawetara jinis birth‑control pills bisa mbantu nyegah kukul ing wanita. Pangobatan awal lan agresif saka kukul nggunakake isotretinoin bisa mbiyantu nyuda komplikasi jangka panjang ing individu.

Pengobatan
Gel Adapalene bisa digunakake kanthi wiyar amarga nyuda sekresi sebum lan duweni efek nyuda kambuh kukul. Gel Adapalene bisa ngganggu kulit yen kakehan ditrapake ing wiwitan. Benzoyl peroxide lan azelaic acid, ing tangan liyane, bisa digunakake ing situs kukul inflamasi amarga mbantu inflamasi. Umumé, perawatan jangka panjang 1 wulan utawa luwih dibutuhake kanggo ndeleng efek.

#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream

#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction
informasi liyane ― Wong jawa
References Diagnosis and treatment of acne 23062156
Jerawat (Acne), kondisi kulit sing paling umum ing Amerika Serikat, minangka masalah kulit inflamasi sing terus-terusan. Perawatan ngarahake kanggo ngatasi patang faktor utama sing nyebabake jerawat (Acne): produksi sebum sing berlebihan, penumpukan sel kulit, kolonisasi Cutibacterium acnes, lan inflamasi. Retinoid topikal kanthi efektif ngatur lesi inflamasi lan non-inflamasi kanthi nyegah lan nyuda komedo (comedone) nalika ngatasi inflamasi. Benzoyl peroksida (benzoyl peroxide), kasedhiya over-the-counter, minangka agen bakterisida tanpa ningkatake resistensi bakteri. Nalika antibiotik (antibiotics) topikal lan lisan bisa digunakake mung, nggabungake karo retinoid topikal nambah efektifitas. Nambahake benzoyl peroksida (benzoyl peroxide) ing terapi antibiotik (antibiotics) nyuda risiko resistensi bakteri. Isotretinoin lisan (isotretinoin), disetujoni kanggo jerawat (Acne) abot lan bandel, diwediake liwat program iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
 Guidelines of care for the management of acne vulgaris 26897386
Pangobatan topikal umum kanggo acne kalebu benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Antibiotik oral wis suwe dadi bagian penting saka perawatan acne, utamane kanggo kasus moderat nganti abot. Dheweke paling apik yen digunakake bebarengan karo retinoid topikal lan BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin kabeh wis nuduhake bukti efektifitas.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
 Acne Vulgaris: Diagnosis and Treatment 31613567
Retinoid topikal tansah dianjurake kanggo nambani kukul. Nalika nggunakake antibiotik sistemik utawa topikal, penting kanggo gabungke karo benzoyl peroxide lan retinoid, nanging mung nganti 12 minggu. Isotretinoin dilindhungi undhang‑undhang kanggo kasus kukul abot sing durung nanggapi perawatan liyane. Sanajan ana sawetara bukti kanggo perawatan fisik kayata laser therapy lan chemical peels, uga pendekatan pelengkap kayata purified bee venom lan diet tartamtu, efektivitasé isih durung mesthi.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
 Effects of Diet on Acne and Its Response to Treatment 32748305 
NIH
Sawetara panaliten wis nyinaoni kepiye macem‑macem panganan mengaruhi acne. Dheweke nemokake manawa wong sing duwe acne sing mangan panganan kanthi beban glikemik sing sithik cenderung duwe acne lesions luwih sithik dibandhingake karo sing mangan panganan kanthi beban glikemik sing dhuwur. Susu uga wis diteliti babagan acne. Katon yen protein tartamtu ing susu bisa nyebabake acne luwih akeh tinimbang isi lemak utawa susu sakabèhé. Riset liyane wis fokus ing asam lemak omega‑3 lan asam γ‑linoleat. Iki nuduhake yen wong sing duwe acne bisa entuk manfaat saka mangan luwih akeh iwak lan lenga sehat kanggo nambah asupan asam lemak kasebut. Panaliten anyar babagan probiotik kanggo acne nuduhake asil sing janjeni, nanging riset luwih akeh dibutuhake kanggo ngonfirmasi temuan awal kasebut.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.