<div id=dx_container class=dx_container><span id=dx_title class=dx_title>Drug eruption</span><span class=dx_title2 style='font-size:12px;text-align:left;padding: 0px 0px 0px 5px;width: 300px;text-overflow: ellipsis;overflow:hidden;white-space:nowrap;word-wrap:break-all;display: inline-block;'><a class='image'><img id='favi' src='./img_wiki/favicon_wikipedia.ico'></a> <a onclick="window.open('https://ca.wikipedia.org/wiki/Erupci%C3%B3_per_f%C3%A0rmac','_blank');"><font color='#007542;'>https://ca.wikipedia.org</font><font color='#555555'>/wiki/Erupció_per_fàrmac</font></a><br></span><div class='comment dx_desc_html'><i class="fas fa-book-medical" style="color:gray;"></i> <b>Drug eruption</b> és una reacció adversa de la pell a un medicament. La majoria de les reaccions cutànies induïdes pel fàrmac són lleus i desapareixen quan es retira el fàrmac ofensor. Tanmateix, poden associar‑se malalties més greus amb lesions d’òrgans, com ara danys hepàtics o renals. Els fàrmacs també poden provocar canvis en els cabells i les ungles, afectar les mucoses o causar picor sense alteracions externes de la pell.<br><br>Les erupcions per medicaments es diagnostiquen principalment a partir de la història clínica i l’examen clínic. També poden ser útils una biòpsia de la pell, anàlisis de sang o proves immunològiques.<br><br>Exemples de fàrmacs comuns que provoquen l’erupció són els antibiòtics i altres fàrmacs antimicrobians, els fàrmacs sulfa, els antiinflamatoris no esteroides (AINE), agents de quimioteràpia per a malalties malignes, anticonvulsivants i psicotròpics.<br><br>○ <b>Diagnòstic i tractament</b><br>Si tens febre (augment de la temperatura corporal), has de buscar atenció mèdica el més aviat possible. S’ha de suspendre el medicament sospitós (per exemple, antibiòtics, antiinflamatoris no esteroides). Abans d’anar a l’hospital, els antihistamínics orals com la cetirizina o la loratadina poden ajudar a alleujar la picor i l’erupció.<br> <a href="javascript:window.open('https://google.com/search?q=Cetirizine%2Bantihistamine','_blank');" style='text-decoration-line:none;'><font color=#007542> #Cetirizine [Zytec]</font></a><span class='retail_link' style='line-height:14px;width:14px;height:14px;font-size:14px;vertical-align:middle'> <a href="javascript:window.open('https://www.amazon.com/s?k=Cetirizine%2Bantihistamine','_blank');"> <img src="https://www.modelderm.com/fav/fav_aws.ico" width=14 height=14 style="display:inline-block; vertical-align: middle;"></a></span><br> <a href="javascript:window.open('https://google.com/search?q=LevoCetirizine%2Bantihistamine','_blank');" style='text-decoration-line:none;'><font color=#007542> #LevoCetirizine [Xyzal]</font></a><span class='retail_link' style='line-height:14px;width:14px;height:14px;font-size:14px;vertical-align:middle'> <a href="javascript:window.open('https://www.amazon.com/s?k=LevoCetirizine%2Bantihistamine','_blank');"> <img src="https://www.modelderm.com/fav/fav_aws.ico" width=14 height=14 style="display:inline-block; vertical-align: middle;"></a></span><br> <a href="javascript:window.open('https://google.com/search?q=Loratadine%2Bantihistamine','_blank');" style='text-decoration-line:none;'><font color=#007542> #Loratadine [Claritin]</font></a><span class='retail_link' style='line-height:14px;width:14px;height:14px;font-size:14px;vertical-align:middle'> <a href="javascript:window.open('https://www.amazon.com/s?k=Loratadine%2Bantihistamine','_blank');"> <img src="https://www.modelderm.com/fav/fav_aws.ico" width=14 height=14 style="display:inline-block; vertical-align: middle;"></a></span><br><br>Anàlisi de sang (CBC, LFT, recompte d'eosinòfils)<br>Esteroides orals i antihistamínics amb recepta mèdica<br><br></div><div id=dx_desc style='font-size:15px;margin-top:15px;margin-bottom:10px;text-decoration: underline;'><i class='fas fa-search'></i> <a onclick="window.open('https://google.com/search?q=Drug+eruption','_blank');"><font color=#555555>Més informació ― Català</font></a></div><div id=dx_desc class='comment' style='display:none'>In medicine, a drug eruption is an adverse drug reaction of the skin. Most drug-induced cutaneous reactions are mild and disappear when the offending drug is withdrawn. These are called "simple" drug eruptions. However, more serious drug eruptions may be associated with organ injury such as liver or kidney damage and are categorized as "complex". Drugs can also cause hair and nail changes, affect the mucous membranes, or cause itching without outward skin changes.</div><!--ADS_WIKI--><div id=thumb_file_container><ul id="images-list"><li><div class='thumb_content'><a onclick="javascript:display_large('./img_wiki/eccc154e1c3851db_31068.webp','https://en.wikipedia.org/wiki/Drug_eruption','https%3A//upload.wikimedia.org/wikipedia/commons/3/3d/Drug_eruptions.jpg','%3Cdiv%20style%3D%22text-align%3Aleft%3Bpadding%3A%200%205px%3B%22%3EDrug%20eruption%20es%20caracteritza%20per%20afectar%20tot%20el%20cos.%3Cbr%3E%3Csub%20style%3D%22line-height%3A1.0em%3Bcolor%3Agray%3B%22%3EDrug%20eruption%20is%20characterized%20by%20affecting%20the%20entire%20body.%3C/sub%3E%3C/div%3E');"><img class=thumb_file id=thumb_file src="./img_wiki/eccc154e1c3851db_31068.webp" onerror="this.onerror=null;this.src='https://d3470w8h9k44xv.cloudfront.net/img_wiki/eccc154e1c3851db_31068.jpg';"></a><a class='image'><img id='favi' src='./img_wiki/favicon_wikipedia.ico' style='padding:0px 3px 0px 0px;vertical-align:text-top;'></a>Drug eruption es caracteritza per afectar tot el cos.</div></li></ul></div><div id=thumb_file_container><ul id="images-list"><li><div class='thumb_content'><a onclick="javascript:display_large('./img_wiki/860a7454193f671a_14666.webp','https://en.wikipedia.org/wiki/Drug_eruption','','%3Cdiv%20style%3D%22text-align%3Aleft%3Bpadding%3A%200%205px%3B%22%3EEn%20els%20casos%20en%20qu%C3%A8%20afecta%20%C3%A0mpliament%20el%20cos%2C%20s%27ha%20de%20considerar%20el%20diagn%C3%B2stic%20de%20Drug%20eruption%20en%20comptes%20de%20dermatitis%20de%20contacte.%3Cbr%3E%3Csub%20style%3D%22line-height%3A1.0em%3Bcolor%3Agray%3B%22%3EIn%20cases%20where%20it%20affects%20the%20body%20widely%2C%20the%20diagnosis%20of%20Drug%20eruption%20should%20be%20considered%20instead%20of%20contact%20dermatitis.%3C/sub%3E%3C/div%3E');"><img class=thumb_file id=thumb_file src="./img_wiki/860a7454193f671a_14666.webp" onerror="this.onerror=null;this.src='https://d3470w8h9k44xv.cloudfront.net/img_wiki/860a7454193f671a_14666.jpg';"></a><a class='image'><i class='fas fa-link' id='favi' style='height:14px;width:14px;vertical-align:text-top;'></i></a>En els casos en què afecta àmpliament el cos, cal considerar el diagnòstic de Drug eruption en comptes de la dermatitis de contacte.</div></li><li><div class='thumb_content'><a onclick="javascript:display_large('./img_wiki/b5ce917c88cb301d_327040.webp','https://en.wikipedia.org/wiki/Acute_generalized_exanthematous_pustulosis','https%3A//upload.wikimedia.org/wikipedia/commons/9/91/Acute_generalized_exanthematous_pustulosis.jpg','%3Cdiv%20style%3D%22text-align%3Aleft%3Bpadding%3A%200%205px%3B%22%3EAGEP%20%28Acute%20generalized%20exanthematous%20pustulosis%29%20%C3%A9s%20un%20tipus%20d%27erupci%C3%B3%20per%20drogues.%3Cbr%3E%3Csub%20style%3D%22line-height%3A1.0em%3Bcolor%3Agray%3B%22%3EAGEP%20%28Acute%20generalized%20exanthematous%20pustulosis%29%20is%20a%20type%20of%20drug%20rash.%3C/sub%3E%3C/div%3E');"><img class=thumb_file id=thumb_file src="./img_wiki/b5ce917c88cb301d_327040.webp" onerror="this.onerror=null;this.src='https://d3470w8h9k44xv.cloudfront.net/img_wiki/b5ce917c88cb301d_327040.jpg';"></a><a class='image'><img id='favi' src='./img_wiki/favicon_wikipedia.ico' style='padding:0px 3px 0px 0px;vertical-align:text-top;'></a>AGEP (Acute generalized exanthematous pustulosis) és un tipus d'erupció per drogues.</div></li></ul></div><!--link_right_before--><div id=link_right><span style='font-size:15px;text-decoration: underline;'><a onclick="window.open('https://bing.com/images/search?q=Drug+eruption','_blank');"><i class='fas fa-images' style='font-size:20px;'></i> Cerca d'imatges</a></span><br></div><div id=link_right><span class='relevance_score' style='display:none;'>relevance score : -100.0%</span></div><span class='dx_title' style=''>References</span><span class="dx_title2" style="font-size:12px;text-align:left;line-height:20px;width:300px;text-overflow:ellipsis;overflow:hidden;white-space:normal;word-wrap:break-all;display:inline-block"><a class="image"><img id="favi" src="https://www.modelderm.com/fav/fav_nih.ico"></a>&nbsp;<a onclick="window.open(&quot;https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286049/&quot;,&quot;_blank&quot;)"><font color="#007542;">Current Perspectives on Severe Drug Eruption</font><font color='#555555'> 34273058</font>&nbsp;<div style="background-color:#005b96; color: white; padding: 2px 3px; display: inline;">NIH</div></a></span><div style="font-size:10px;line-height:15px;padding:0px;text-align:left;margin-bottom:5px;">Les reaccions cutànies causades per medicaments, conegudes com a erupcions de drogues, de vegades poden ser greus. Aquestes reaccions greus, anomenades severe cutaneous adverse drug reactions (SCARs), es consideren potencialment mortals. Inclouen condicions com Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP) i drug reaction with eosinophilia and systemic symptoms (DRESS). Tot i que les SCARs són rares, al voltant del 2 % dels pacients hospitalitzats les experimenten. <br><span style='color:gray;'>Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.</span></div><span class="dx_title2" style="font-size:12px;text-align:left;line-height:20px;width:300px;text-overflow:ellipsis;overflow:hidden;white-space:normal;word-wrap:break-all;display:inline-block"><a class="image"><img id="favi" src="https://www.modelderm.com/fav/fav_nih.ico"></a>&nbsp;<a onclick="window.open(&quot;https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481251/&quot;,&quot;_blank&quot;)"><font color="#007542;">Fixed drug eruption - Case reports</font><font color='#555555'> 35918090</font>&nbsp;<div style="background-color:#005b96; color: white; padding: 2px 3px; display: inline;">NIH</div></a></span><div style="font-size:10px;line-height:15px;padding:0px;text-align:left;margin-bottom:5px;">Una dona de 31 anys va visitar el departament de dermatologia amb una taca vermella indolora a la part superior del peu dret. Havia pres una dosi de doxiciclina (100 mg) el dia anterior, després del tractament amb làser de picosegons per a les cicatrius d&#x27;acne. L&#x27;any passat, havia tingut un problema similar al mateix lloc després d&#x27;haver pres la mateixa dosi de doxiciclina com a tractament post‑làser. No té antecedents mèdics significatius ni cap altre símptoma, com ara febre, ni a nivell local ni general. <br><span style='color:gray;'>A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.</span></div><span class="dx_title2" style="font-size:12px;text-align:left;line-height:20px;width:300px;text-overflow:ellipsis;overflow:hidden;white-space:normal;word-wrap:break-all;display:inline-block"><a class="image"><img id="favi" src="https://www.modelderm.com/fav/fav_nih.ico"></a>&nbsp;<a onclick="window.open(&quot;https://www.ncbi.nlm.nih.gov/books/NBK459323/&quot;,&quot;_blank&quot;)"><font color="#007542;">Stevens-Johnson Syndrome</font><font color='#555555'> 29083827</font>&nbsp;<div style="background-color:#005b96; color: white; padding: 2px 3px; display: inline;">NIH</div></a></span><div style="font-size:10px;line-height:15px;padding:0px;text-align:left;margin-bottom:5px;">Stevens-Johnson syndrome (SJS) i toxic epidermal necrolysis (TEN) són dues formes de reacció cutània greu, diferents d'altres afeccions de la pell com l'eritema multiforme major i la síndrome de la pell escaldada per estafilococ, així com les reaccions als medicaments. SJS/TEN és una reacció rara però greu que causa danys generalitzats a la pell i a les mucoses, sovint acompanyada de símptomes sistèmics. En més del 80 % dels casos, els medicaments són la causa. <br><span style='color:gray;'>Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome­, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.</span></div></div>